• Investigating the efficacy of a moving bed biofilm reactor for the removal of the antiretrovirals tenofovir, emtricitabine, nevirapine, ritonavir and efavirenz from synthetic wastewater 

  Mokgope, Herman D. (Vaal University of Technology, 2022-04)

  South Africa utilises more antiretroviral (ARV) compounds per capita than any other nation in the fight against Human Immune Deficiency Virus (HIV) or acquired immunodeficiency syndrome (AIDS). Considering the main entrance ...
• The effect of a sugar sweetened beverage diet on DNA methylation in a CACO-2 cell line in vitro 

  Ndhlovu, Lesego (Vaal University of Technology, 2020-12)

  Obesity has steadily increased and represents a major public health problem worldwide, reducing quality of life and causing a range of health problems. Obesity has emerged as the fifth leading risk of global deaths. Annually, ...
• Synthesis, characterisation and assessment of antimicrobial activity of doped zinc oxide nanoparticles against selected waterborne pathogens 

  Volofu, Nomasamariya Elsie (Vaal University of Technology, 2019-07-29)

  The aim of the study is to synthesise, characterize and assess the antimicrobial activity of cobalt oxide, zinc oxide and cobalt-doped zinc oxide nanoparticles against selected waterborne pathogenic fungi (yeasts and moulds) ...
• The prevalence of HBV, HTLV, HIV and concurrent infections in blood recipients of the South African National Blood Service (SANBS) 

  Willemse, Reynier (Vaal University of Technology, 2020-12)

  Background: Currently, the South African National Blood Services are not testing for HTLV and HTLV screening is not mandated by the WHO or by regulatory standards in South Africa. Looking at the uniquely high prevalence ...
• Assessing the pollutant removal efficiency of a wetland as a polishing treatment for municipal wastewater 

  Mphuthi, Betty Refilwe (Vaal University of Technology, 2021-02-16)

  Pollution of aquatic systems by wastewater containing pathogens, heavy metals and high concentrations of nutrients is of great concern due the ecological risks they impose. The toxic effects of metals may occur even at low ...
• The effect of crude water extracts of Tulbaghia violacea Harv. on scaffolds with cardiovascular applications 

  Madike, Lerato Nellvecia (Vaal University of Technology, 2020-02)

  Tulbaghia violacea Harv. has found extensive uses in traditional medicine for the treatment of numerous ailments among which are tuberculosis, oesophageal cancer, diabetes and cardiovascular diseases. Current reports show ...
• To establish the prevalence of MTHFR C677T polymorphism in correlation with homocysteine metabolic markers in a black elderly community, in Sharpeville, Gauteng province in South Africa 

  Pule, Pule Bongani (Vaal University of Technology, 2021)

  Background: Increased serum homocysteine is well known as an independent cardiovascular risk factor. Hyperhomocysteinemia may be due to several factors such as nutritional deficiencies and genetics. The MTHFR C677T ...
• The effects of solar irradiated Salmonella Typhimurium and campylobacter jejuni on the proliferation and activation of macrophages in vitro 

  Chihomvu, Patience (Vaal University of Technology, 2019-12)

  Salmonella enterica serovar Typhimurium and Campylobacter jejuni are the leading causes of Salmonellosis and Campylobacteriosis that is characterised by gastroenteritis. These waterborne diseases can be easily prevented ...
• Engineering of an enzyme cocktail for biodegradation of petroleum hydrocarbons based on known enzymatic pathways and metagenomic techniques 

  Baburam, Cindy (Vaal University of Technology, 2020-07)

  Hydrocarbon pollution is becoming a growing environmental concern in South Africa and globally. This inadvertently supports the need to identify enzymes for their targeted degradation. The search for novel biocatalysts ...
• Investigation of seasonal prevalence of low pathogenic avian influenza (LPAI) in a heterogeneous wild waterfowl population in Pretoria. 

  Phiri, Thandeka P. (Vaal University of Technology, 2018-06)

  Influenza-A virus is a single stranded negative sense RNA virus that is a member of a Orthomyxoviridae group. The virus is diverse and consists of 16 haemagglutinin (H) and 9 neuraminidase (N) glycoproteins subtypes that ...
• Mining of genes encoding for DNA-manipulating enzymes from hot springs using metagenomic techniques. 

  Mokoena, Morena India (Vaal University of Technology, 2019-09)

  The use of conventional culture-based approach results in vast majority of microbes (90 - 99%) unaccounted for. However, over the past years, the use of metagenomics, which is a culture-independent comprehensive approach ...
• Establishing the correlation between R353Q polymorphism and haemostatic markers in a black elderly community of Sharpeville Gauteng Province South Africa. 

  Rodrigue, Tagne Wambo Joseph (Vaal University of Technology, 2019)

  Background: In a group of the elderlies (older person) in Sharpeville, Gauteng, South Africa, the majority live in poverty with a poor nutritional status. This makes them susceptible to develop infectious diseases as well ...
• Sequence and function based screening of the goat rumen metagenome for novel amylases. 

  Rabapane, Kgodiso Judith (Vaal University of Technology, 2019-09)

  During one of our preliminary studies in 2015, metagenomic DNA extracted from the goat rumen was sequenced and the in silico mining of the biorefining enzyme showed the presence of significant number of different ...
• The evaluation of whole blood cytokine assay for diagnosis of M.tuberculosis infection in South African children with household tuberculosis contact. 

  Masilo, J. M. (Vaal University of Technology, 2019-04)

  Background: There are critical unmet needs for improved strategies in the detection and diagnosis of M.tuberculosis infection in children, and for prevention of tuberculosis disease in children. Bacillus Calmette-Guérin ...
• Correlating the prevalence of C174G polymorphism with IL-6, TNF-α and Hs-CRP in an elderly black South African population. 

  Valentine, Jessica (Vaal University of Technology, 2019-03)

  Cardiovascular diseases (CVDs) are the leading cause of death worldwide, and the prevalence thereof is on the rise in developing countries due to the demographic transition and urbanization. The inflammatory process, ...
• Determining the effectiveness of water treatment process barriers for the removal of viruses in drinking water. 

  Setlhare, Khomotso Charity (2018)

  The presence of enteric viruses in drinking water poses a health risk to consumers. It is therefore very important for drinking water suppliers to provide water that is pathogen free and fit for human consumption. This can ...
• Sequence and function-based screening of goat rumen metagenome for novel lipases 

  Mukendi, Mujinga Grace (Vaal University of Technology, 2019-09)

  Lipases have been one of the important biocatalysts that catalyse the transformation of lipids to yield very important products that can be of beneficial in food, agriculture, pharmaceutical medicine and for the biodiesel ...
• Identification of the dominant bacteria associated with the spoilage of UHT full cream milk 

  Moloto, Phuti Gladys (Vaal University of Technology, 2016-11)

  The Organization for Economic Co-operation and Development (OECD) and the Food and Agriculture Organization (FAO) of the United Nations predict that milk production and the dairy sector will remain one of the fastest-growing ...
• The effects of biofouling on a reverse osmosis membrane purification system at Sasol, Sasolburg 

  Takaidza, Samkeliso (Vaal University of Technology, 2011-06)

  Reverse osmosis (RO) membranes are widely used in water purification. The presence of biofilms in water and industrial water purification systems is prevalent. As a result, biofouling which is a biofilm problem causes ...
• A Comparative study between the prevalence of MTHFR A1298C SNP and homocysteine metabolism in an elderly black South African population 

  Dippenaar, Luzanne (2018-08)

  Background: Cardiovascular diseases are one of the most common causes of death worldwide. This is not only a problem in developed countries, it is of major concern for public health in developing countries as well. Increased ...

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